Early in his career, Milloy worked for a company called Multinational Business Services, a Washington lobby shop that Philip Morris described as its "primary contact” on the issue of secondhand cigarette smoke in the early 1990s. Later, he became executive director of The Advancement of Sound Science Coalition (TASSC), an organization that was covertly created by Philip Morris for the express purpose of generating scientific controversy regarding the link between secondhand smoke and cancer.

Bei "Source Watch" steht auch was zu TASSC, welche Rolle George L. Carlo spielte, aber auch welchen Einfluss TASSC bzw. Philip Morris auf Milloys Seite "Junk Science" hat.